Journal of Dentistry
Volume 38, Issue 2 , Pages 153-157, February 2010

Effect of a single application of TiF4 and NaF varnishes and solutions on dentin erosion in vitro

  • Ana Carolina Magalhães

      Affiliations

    • Department of Biological Sciences, Bauru School of Dentistry-USP, Bauru, SP 17012-910, Brazil
    • Corresponding Author InformationCorresponding author at: Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru. Al. Octávio Pinheiro Brisolla, 9-75 Bauru, SP 17012-901, Brazil. Tel.: +55 14 32358246; fax: +55 14 32271486.
  • ,
  • Flávia Mauad Levy

      Affiliations

    • Department of Biological Sciences, Bauru School of Dentistry-USP, Bauru, SP 17012-910, Brazil
  • ,
  • Daniela Rios

      Affiliations

    • Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry-USP, Bauru, SP 17012-910, Brazil
  • ,
  • Marília Afonso Rabelo Buzalaf

      Affiliations

    • Department of Biological Sciences, Bauru School of Dentistry-USP, Bauru, SP 17012-910, Brazil

Received 14 August 2009; received in revised form 24 September 2009; accepted 28 September 2009. published online 05 October 2009.

Abstract 

Objectives

This in vitro study aimed to analyse the effect of a single application of TiF4 and NaF varnishes and solutions to protect against dentin erosion.

Methods

Bovine root dentin samples were pre-treated with NaF-Duraphat varnish (2.26%F, pH 4.5), NaF/CaF2-Duofluorid varnish (5.63%F, pH 8.0), NaF-experimental varnish (2.45%F, pH 4.5), TiF4-experimental varnish (2.45%F, pH 1.2), NaF solution (2.26%F, pH 4.5), TiF4 solution (2.45%F, pH 1.2) and placebo varnish (pH 5.0, no-F varnish control). Controls remained untreated. Ten samples in each group were then subjected to an erosive demineralisation (Sprite Zero, 4× 90s/day) and remineralisation (artificial saliva, between the erosive cycles) cycling for 5 days. Dentin loss was measured profilometrically after pre-treatment and after 1, 3 and 5 days of de-remineralisation cycling. The data were statistically analysed by two-way ANOVA and Bonferroni's post hoc test (p<0.05).

Results

After pre-treatment, TiF4 solution significantly induced surface loss (1.08±0.53μm). Only Duraphat reduced the dentin loss overtime, but it did not significantly differ from placebo varnish (at 3rd and 5th days) and TiF4 varnish (at 3rd day).

Conclusions

Duraphat varnish seems to be the best option to partially reduce dentin erosion. However, the maintenance of the effects of this treatment after successive erosive challenges is limited.

Keywords: Dentin, Erosion, Fluoride

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PII: S0300-5712(09)00232-2

doi:10.1016/j.jdent.2009.09.015

Journal of Dentistry
Volume 38, Issue 2 , Pages 153-157, February 2010