Effect of sodium, amine and stannous fluoride at the same concentration and different pH on in vitro erosion

Wiegand, Annette; Bichsel, Dominique; Magalhães, Ana Carolina; Becker, Klaus; Attin, Thomas

doi:10.1016/j.jdent.2009.03.020

« Previous Next »Journal of Dentistry
Volume 37, Issue 8 , Pages 591-595, August 2009

Effect of sodium, amine and stannous fluoride at the same concentration and different pH on in vitro erosion

Annette Wiegand
- Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Plattenstrasse 11, CH-8032 Zürich, Switzerland
- Corresponding author. Tel.: +41 44 634 32 71; fax: +41 44 634 43 08.
Dominique Bichsel
- Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Plattenstrasse 11, CH-8032 Zürich, Switzerland
Ana Carolina Magalhães
- Department of Biological Sciences, Bauru Dental School, University of São Paulo, Alameda Octávio Pinheiro Brisolla 9-75, Bauru, SP, Brazil
Klaus Becker
- Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Plattenstrasse 11, CH-8032 Zürich, Switzerland
Thomas Attin
- Clinic for Preventive Dentistry, Periodontology and Cariology, University of Zürich, Plattenstrasse 11, CH-8032 Zürich, Switzerland

Received 12 January 2009; received in revised form 26 March 2009; accepted 28 March 2009. published online 06 April 2009.

Abstract

Objective

This study aimed to compare the effects 0.5% and 1% sodium, amine and stannous fluoride at different pH on enamel erosion in vitro.

Methods

Bovine enamel samples were submitted to a cyclic de- and remineralisation for 3 days. Each day, the samples were exposed for 120min to pooled human saliva and subsequently treated with one of the fluoride solutions for 3min: amine fluoride (AmF, 0.5% and 1% F⁻), sodium fluoride (NaF, 0.5% and 1% F⁻), each at pH 3.9 and 7.0, and stannous fluoride (SnF₂, 0.5% and 1% F⁻), at pH: 3.9. Additionally, two groups were treated with fluoride-free placebo solutions (pH: 3.9 and 7.0) and one group served as control (no fluoridation). Ten specimens each group were inserted in a so-called artificial mouth and eroded six times daily with hydrochloric acid (pH 2.6) for 90s each intermitted by exposure to artificial saliva (1h). After 3 days, enamel loss was analyzed profilometrically and evaluated statistically by ANOVA.

Results

Only the acidic 0.5% and 1% SnF₂ and 1% AmF solutions were able to reduce erosive enamel loss significantly, while all other solutions and placebos did not differ significantly from the control. Between the acidic SnF₂ and the 1% AmF solutions no significant differences could be detected.