The effect of casein phosphopeptide–amorphous calcium phosphate on erosive enamel and dentine wear by toothbrush abrasion

Abstract 

Objective

In addition to its role as a remineralizing agent in preventing dental caries, calcium product (CPP–ACP) delivered as a mousse (Tooth Mousse^®, TM) can reduce erosion of enamel and dentine. The aim of this study was to determine whether CPP–ACP could also reduce erosive tooth wear involving toothbrush abrasion.

Methods

Flat, polished enamel and dentine specimens (n=72) were subjected to 10 wear regimes, with each regime involving erosion in 0.3% citric acid (pH 3.2) for 10min followed by toothbrush abrasion in a slurry of fluoride-free toothpaste and artificial saliva (1:3 ratio by weight) under a load of 2N for 200 cycles. The specimens were immersed in artificial saliva for 2h between wear regimes. In the experimental group 1, TM (containing CPP–ACP) was applied at the beginning of each wear episode for 5min whereas TM− (without CPP–ACP) was applied in the experimental group 2. No mousse was applied in the control group.

Results

TM significantly reduced enamel wear (mean±S.E., 1.26±0.33μm in the experimental group 1 vs 3.48±0.43μm in the control group) and dentine wear (2.16±0.89μm in the experimental group 1 vs 10.29±1.64μm in the control group), and dentine wear was significantly less in the experimental group 1 than in the experimental group 2 (5.75±0.98μm).

Conclusion

The finding that TM reduced erosive tooth wear involving toothbrush abrasion, probably by remineralizing and lubricating eroded tooth surfaces, may have implications in the management of tooth wear.

Keywords: Abrasion, Erosion, CPP–ACP, Remineralization, Lubrication