Effect of fluoridated bleaching gels on the remineralization of predemineralized bovine enamel in vitro

Tschoppe, Peter; Neumann, Konrad; Mueller, Jan; Kielbassa, Andrej M.

doi:10.1016/j.jdent.2008.11.001

« Previous Next »Journal of Dentistry
Volume 37, Issue 2 , Pages 156-162, February 2009

Effect of fluoridated bleaching gels on the remineralization of predemineralized bovine enamel in vitro

Peter Tschoppe
- Department of Operative Dentistry and Periodontology, University School of Dental Medicine, CharitéCentrum 3, Germany
- Corresponding author at: Abteilung für Zahnerhaltungskunde und Parodontologie, CharitéCentrum 3 für Zahn-, Mund- und Kieferheilkunde, Charité - Universitätsmedizin Berlin, Aßmannshauser Strasse 4-6, 14197 Berlin, Deutschland, Germany. Tel.: +49 30 450 662 327/332; fax: +49 30 450 562 932.
Konrad Neumann
- Department of Biometry and Clinical Epidemiology, CharitéCentrum 4, Charité - Universitätsmedizin Berlin, Germany
Jan Mueller
- Department of Operative Dentistry and Periodontology, University School of Dental Medicine, CharitéCentrum 3, Germany
Andrej M. Kielbassa
- Department of Operative Dentistry and Periodontology, University School of Dental Medicine, CharitéCentrum 3, Germany

Received 4 September 2008; received in revised form 30 October 2008; accepted 3 November 2008.

Abstract

Objectives

This study evaluated possible differences regarding the remineralization of predemineralized enamel after exposure to fluoridated or non-fluoridated bleaching gels.

Methods

120 enamel specimens were prepared from sixty bovine incisors; before and after demineralization (37°C; pH 4.95; 10d), one-quarter of each specimen's surface was covered with nail varnish (control sound/demineralized). Subsequently, the specimens were stored for 16h daily in a remineralizing solution (pH 7.0; 14d), while for the remaining time (8h) various bleaching gels were applied: (1) no treatment (control), (2) Opalescence regular (O, Ultradent), (3) Opalescence PF (O-PF), (4) Nite White ACP (NW-ACP, Discus Dental) and (5) Nite White ACPF (NW-ACPF). Following, half of the bleached parts were nail-varnished and stored for another 3-weeks period in a remineralizing solution. Differences in mineral losses (ΔΔZ) and lesion depths (ΔLD) before and after treatment/remineralization period were evaluated from microradiographs. ΔΔZ_surface values (mineral loss of the outer 18μm of the lesion) were calculated.

Results

After 2 and 5 weeks ΔΔZ/ΔLD values of the bleaching groups did not differ significantly from the controls. Treatment with NW-ACPF for 2 weeks resulted in significantly lower ΔΔZ values compared to NW-ACP (p=0.032) and NW-ACPF in higher values than Opalescence regular (p=0.006). Two weeks treatment with O and O-PF resulted in decreased ΔΔZ_surface values compared to control (p<0.0005), whereas with NW-ACPF no significant differences could be observed (p=0.062). Application of NW-ACP induced significantly increased ΔΔZ_surface values compared to control (p=0.001).