Journal of Dentistry
Volume 36, Issue 4 , Pages 268-271 , April 2008

Saliva variations in gastro-oesophageal reflux disease

  • G. Campisi

      Affiliations

    • Department Oral Sciences, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy
    • Corresponding Author InformationCorresponding author. Fax: +39 091 655 2236.
    • ,
  • L. Lo Russo

      Affiliations

    • Department Oral Sciences, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy
    • ,
  • C. Di Liberto

      Affiliations

    • Department Oral Sciences, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy
    • ,
  • F. Di Nicola

      Affiliations

    • Department Oral Sciences, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy
    • ,
  • D. Butera

      Affiliations

    • Departments of Pharmaceutical, Toxicological and Biological Chemistry, and Medical Biotechnologies and Forensic Medicine, University of Palermo, Italy
    • ,
  • S. Vigneri

      Affiliations

    • Institute of Internal Medicine and Geriatrics, University of Palermo, Italy
    • ,
  • D. Compilato
    • ,
  • L. Lo Muzio

      Affiliations

    • Department of Surgical Sciences, University of Foggia, Italy
    • ,
  • O. Di Fede

      Affiliations

    • Department Oral Sciences, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy

Received 6 July 2007 ,Revised 7 January 2008 ,Accepted 8 January 2008.

References 

  1. Sarosiek J, McCallum RW. Mechanisms of oesophageal mucosal defence. Bailliere's Best Practice & Research. Clinical Gastroenterology. 2000;14:701–717
  2. Bouchoucha M, Callais F, Renard P, Ekindjian OG, Cugnenc PH, Barbier JP. Relationship between acid neutralization capacity of saliva and gastro-oesophageal reflux. Archives of Physiology and Biochemistry. 1997;105:19–26
  3. Costa HO, Neto OM, Eckley CA. Is there a relationship between the pH and volume of saliva and esophageal pH-metry results?. Dysphagia. 2005;20:175–181
  4. Helm JF. Role of saliva in esophageal function and disease. Dysphagia. 1989;4:76–84
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  10. Campisi G, Di Fede O, Roccia P, Di Nicola F, Falaschini S, Lo Muzio L. Saliva: its value as biological matrix and current methods of sampling. European Journal of Inflammation. 2006;4:11–19
  11. Helm JF, Dodds WJ, Hogan WJ. Salivary response to esophageal acid in normal subjects and patients with reflux esophagitis. Gastroenterology. 1987;93:1393–1397
  12. Helm JF, Dodds WJ, Pelc LR, Palmer DW, Hogan WJ, Teeter BC. Effect of esophageal emptying and saliva on clearance of acid from the esophagus. New England Journal of Medicine. 1984;310:284–288
  13. Dutta SK, Matossian HB, Meirowitz RF, Vaeth J. Modulation of salivary secretion by acid infusion in the distal esophagus in humans. Gastroenterology. 1992;103:1833–1841
  14. Brown CM, Snowdon CF, Slee B, Sandle LN, Rees WD. Effect of topical oesophageal acidification on human salivary and oesophageal alkali secretion. Gut. 1995;36:649–653
  15. Anderson P, Hector MP, Rampersad MA. Critical pH in resting and stimulated whole saliva in groups of children and adults. International Journal of Paediatric Dentistry. 2001;11:266–273
  16. Edgar WM. Saliva: its secretion, composition and functions. British Dental Journal. 1992;172:305–312
  17. Kongara K, Varilek G, Soffer EE. Salivary growth factors and cytokines are not deficient in patients with gastroesophageal reflux disease or Barrett's esophagus. Digestive Diseases and Sciences. 2001;46:606–609
  18. Moazzez R, Bartlett D, Anggiansah A. Dental erosion, gastro-oesophageal reflux disease and saliva: how are they related?. Journal of Dentistry. 2004;32:489–494
  19. Sonnenberg A, Steinkamp U, Weise A, Berges W, Wienbeck M, Rohner HG, et al. Salivary secretion in reflux esophagitis. Gastroenterology. 1982;83:889–895
  20. Sarosiek J, Scheurich CJ, Marcinkiewicz M, McCallum RW. Enhancement of salivary esophagoprotection: rationale for a physiological approach to gastroesophageal reflux disease. Gastroenterology. 1996;110:675–681

PII: S0300-5712(08)00019-5

doi: 10.1016/j.jdent.2008.01.003

Journal of Dentistry
Volume 36, Issue 4 , Pages 268-271 , April 2008

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