Journal of Dentistry
Volume 36, Issue 2 , Pages 104-116 , February 2008

The application of ozone in dentistry: A systematic review of literature

  • Amir Azarpazhooh

      Affiliations

    • Department of Endodontics and Community Dental Health Services Research Unit, Faculty of Dentistry, University of Toronto, Room #521A, 124 Edward Street, Toronto, ON, M5G 1G6 Canada
    • Corresponding Author InformationCorresponding author. Tel.: +1 416 979 4907x4429; fax: +1 416 979 4936.
    • ,
  • Hardy Limeback

      Affiliations

    • Department of Preventive Dentistry, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, ON, M5G 1G6 Canada

Received 10 May 2007 ,Revised 9 November 2007 ,Accepted 18 November 2007.

References 

  1. Grootveld M, Baysan A, Sidiiqui N, Sim J, Silwood C, Lynch E. History of the clinical applications of ozone. In:  Lynch E editors. Ozone: the revolution in dentistry. London: Quintessence Publishing Co.; 2004;p. 23–30
  2. American Chemical Society. Ozone: molecule with a split personality. Available from: http://www.chemistry.org/portal/a/c/s/1/feature_tea.html?id=fd67fec2abd211d6e1e16ed9fe800100; 2001 [cited July 22, 2006].
  3. Bocci V. How ozone acts and how it exerts therapeutic effects. In:  Lynch E editors. Ozone: the revolution in dentistry. London: Quintessence Publishing Co.; 2004;p. 15–22
  4. Solomon S. Stratospheric ozone depletion: a review of concepts and history. Reviews of Geophysics. 1999;37:275–316
  5. Nagayoshi M, Kitamura C, Fukuizumi T, Nishihara T, Terashita M. Antimicrobial effect of ozonated water on bacteria invading dentinal tubules. Journal of Endodontics. 2004;30:778
  6. Ebensberger U, Pohl Y, Filippi A. PCNA-expression of cementoblasts and fibroblasts on the root surface after extraoral rinsing for decontamination. Dental Traumatology. 2002;18:262
  7. Nagayoshi M, Fukuizumi T, Kitamura C, Yano J, Terashita M, Nishihara T. Efficacy of ozone on survival and permeability of oral microorganisms. Oral Microbiology & Immunology. 2004;19:240
  8. Sittig M. Handbook of toxic and hazardous chemicals and carcinogens. 2nd ed.. Park Ridge, NJ: Noyes Data Corporation; 1985;
  9. Arita M, Nagayoshi M, Fukuizumi T, Okinaga T, Masumi S, Morikawa M, et al. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. Oral Microbiology & Immunology. 2005;20:206
  10. Kim JG, Yousef AE, Dave S. Application of ozone for enhancing the microbiological safety and quality of foods: a review. Journal of Food Protection. 1999;62:1071–1087
  11. Celiberti P, Pazera P, Lussi A. The impact of ozone treatment on enamel physical properties. American Journal of Dentistry. 2006;19:67–72
  12. Holmes J. Clinical reversal of root caries using ozone, double-blind, randomised, controlled 18-month trial. Gerodontology. 2003;20:106–114
  13. AbuNaba’a L, Al Shorman H, Holmes J, Peterson L, Tagami J, Lynch E. Evidence-based research into ozone treatment in dentistry: an overview. In:  Lynch E editors. Ozone: the revolution in dentistry. London: Quintessence Publishing Co.; 2004;p. 73–115
  14. Margolis HC, Moreno EC, Murphy BJ. Importance of high pKa acids in cariogenic potential of plaque. Journal of Dental Research. 1985;64:786–792
  15. Bocci V. Ozone as Janus: this controversial gas can be either toxic or medically useful. Mediators of Inflammation. 2004;13:3
  16. Baysan A, Lynch E. Antimicrobial effects of ozone on caries. In:  Lynch E editors. Ozone: the revolution in dentistry. London: Quintessence Publishing Co.; 2004;p. 165–172
  17. Bocci V. Ozone. The Netherlands: Springer; 2005;
  18. Baysan A, Whiley RA, Lynch E. Antimicrobial effect of a novel ozone-generating device on micro-organisms associated with primary root carious lesions in vitro. Caries Research. 2000;34:498–501
  19. Rickard GD, Richardson R, Johnson T, McColl D, Hooper L. Ozone therapy for the treatment of dental caries. Cochrane Database of Systematic Reviews. 2004;CD004153
  20. Abu-Naba’a L. Management of primary occlusal pit and fissure caries using ozone. Belfast, UK: Queen's University; 2003;
  21. Huth KC, Paschos E, Brand K, Hickel R. Effect of ozone on non-cavitated fissure carious lesions in permanent molars: a controlled prospective clinical study. American Journal of Dentistry. 2005;18:223–228
  22. Dahnhardt JE, Jaeggi T, Lussi A. Treating open carious lesions in anxious children with ozone: a prospective controlled clinical study. American Journal of Dentistry. 2006;19:267–270
  23. Baysan A. Management of primary root caries using ozone therapies. London: Bart's and The London Queen Mary's School of Medicine and Dentistry; 2002;
  24. Silva BB, Severo NB, Maltz M. Validity of diode laser to monitor carious lesions in pits and fissures. Journal of Dentistry. 2007;35:679
  25. Virajsilp V, Thearmontree A, Aryatawong S, Paiboonwarachat D. Comparison of proximal caries detection in primary teeth between laser fluorescence and bitewing radiography. Pediatric Dentistry. 2005;27:493–499
  26. Tranaeus S, Lindgren LE, Karlsson L, Angmar-Mansson B. In vivo validity and reliability of IR fluorescence measurements for caries detection and quantification. Swedish Dental Journal. 2004;28:173–182
  27. Baseren NM, Gokalp S. Validity of a laser fluorescence system (DIAGNOdent) for detection of occlusal caries in third molars: an in vitro study. Journal of Oral Rehabilitation. 2003;30:1190–1194
  28. Bamzahim M, Shi XQ, Angmar-Mansson B. Occlusal caries detection and quantification by DIAGNOdent and electronic caries monitor: in vitro comparison. Acta Odontologica Scandinavica. 2002;60:360–364
  29. Alwas-Danowska HM, Plasschaert AJ, Suliborski S, Verdonschot EH. Reliability and validity issues of laser fluorescence measurements in occlusal caries diagnosis. Journal of Dentistry. 2002;30:129–134
  30. Wicht MJ, Haak R, Stutzer H, Strohe D, Noack MJ. Intra- and inter-examiner variability and validity of laser fluorescence and electrical resistance readings on root surface lesions. Caries Research. 2002;36:241–248
  31. Pinelli C, Campos Serra M, de Castro Monteiro Loffredo L. Validity and reproducibility of a laser fluorescence system for detecting the activity of white-spot lesions on free smooth surfaces in vivo. Caries Research. 2002;36:19–24
  32. Takamori K, Hokari N, Okumura Y, Watanabe S. Detection of occlusal caries under sealants by use of a laser fluorescence system. Journal of Clinical Laser Medicine & Surgery. 2001;19:267–271
  33. Tam LE, McComb D. Diagnosis of occlusal caries. II. Recent diagnostic technologies. Journal (Canadian Dental Association). 2001;67:459–463
  34. Shi XQ, Welander U, Angmar-Mansson B. Occlusal caries detection with KaVo DIAGNOdent and radiography: an in vitro comparison. Caries Research. 2000;34:151–158
  35. Lussi A, Imwinkelried S, Pitts N, Longbottom C, Reich E. Performance and reproducibility of a laser fluorescence system for detection of occlusal caries in vitro. Caries Research. 1999;33:261–266
  36. Ricketts DN, Kidd EA, Wilson RF. The electronic diagnosis of caries in pits and fissures: site-specific stable conductance readings or cumulative resistance readings?. Caries Research. 1997;31:119–124
  37. Ricketts DN, Kidd EA, Wilson RF. The effect of airflow on site-specific electrical conductance measurements used in the diagnosis of pit and fissure caries in vitro. Caries Research. 1997;31:111–118
  38. Ricketts DN, Kidd EA, Wilson RF. A re-evaluation of electrical resistance measurements for the diagnosis of occlusal caries. British Dental Journal. 1995;178:11–17
  39. Petrie A, Bulman JS, Osborn JF. Further statistics in dentistry. Part 7. Repeated measures. British Dental Journal. 2003;194:17–21
  40. Brazzelli M, McKenzie L, Fielding S, Fraser C, Clarkson J, Kilonzo M, et al. Systematic review of the effectiveness and cost-effectiveness of HealOzone for the treatment of occlusal pit/fissure caries and root caries. Health Technology Assessment (Winchester, England). 2006;10:50
  41. Muller P, Guggenheim B, Schmidlin PR. Efficacy of gasiform ozone and photodynamic therapy on a multispecies oral biofilm in vitro. European Journal of Oral Sciences. 2007;115:77–80
  42. Walker JT, Bradshaw DJ, Fulford MR, Marsh PD. Microbiological evaluation of a range of disinfectant products to control mixed-species biofilm contamination in a laboratory model of a dental unit water system. Applied & Environmental Microbiology. 2003;69:3327
  43. Huth KC, Jakob FM, Saugel B, Cappello C, Paschos E, Hollweck R, et al. Effect of ozone on oral cells compared with established antimicrobials. European Journal of Oral Sciences. 2006;114:435–440
  44. Murakami H, Mizuguchi M, Hattori M, Ito Y, Kawai T, Hasegawa J. Effect of denture cleaner using ozone against methicillin-resistant Staphylococcus aureus and E. coli T1 phage. Dental Materials Journal. 2002;21:53–60
  45. Estrela C, Estrela CR, Decurcio Dde A, Silva JA, Bammann LL. Antimicrobial potential of ozone in an ultrasonic cleaning system against Staphylococcus aureus. Brazilian Dental Journal. 2006;17:134–138
  46. Oizumi M, Suzuki T, Uchida M, Furuya J, Okamoto Y. In vitro testing of a denture cleaning method using ozone. Journal of Medical and Dental Sciences. 1998;45:135–139
  47. Estrela C, Estrela CRA, Decurcio DA, Hollanda ACB, Silva JA. Antimicrobial efficacy of ozonated water, gaseous ozone, sodium hypochlorite and chlorhexidine in infected human root canals. International Endodontic Journal. 2007;40:85–93
  48. Hems RS, Gulabivala K, Ng YL, Ready D, Spratt DA. An in vitro evaluation of the ability of ozone to kill a strain of Enterococcus faecalis. International Endodontic Journal. 2005;38:22
  49. Polydorou OPK, Hahn P. Antibacterial effect of an ozone device and its comparison with two dentin-bonding systems. European Journal of Oral Sciences. 2006;114:349–353
  50. Schmidlin PR, Zimmermann J, Bindl A. Effect of ozone on enamel and dentin bond strength. The Journal of Adhesive Dentistry. 2005;7:29–32
  51. Suzuki T, Oizumi M, Furuya J, Okamoto Y, Rosenstiel SF. Influence of ozone on oxidation of dental alloys. The International Journal of Prosthodontics. 1999;12:179–183
  52. Krozer A, Hall J, Ericsson l. Chemical treatment of machined titanium surfaces: an in vitro study. Clinical Oral Implants Research. 1999;10:204–211
  53. Steinhart H, Schulz S, Mutters R. Evaluation of ozonated oxygen in an experimental animal model of osteomyelitis as a further treatment option for skull-base osteomyelitis. European Archives of Oto-rhino-laryngology. 1999;256:153–157
  54. Stubinger S, Sader R, Filippi A. The use of ozone in dentistry and maxillofacial surgery: a review. Quintessence International. 2006;37:353–359

PII: S0300-5712(07)00241-2

doi: 10.1016/j.jdent.2007.11.008

Journal of Dentistry
Volume 36, Issue 2 , Pages 104-116 , February 2008

Article Tools