Journal of Dentistry
Volume 35, Issue 11 , Pages 871-874 , November 2007

Chitosan-containing gum chewing accelerates antibacterial effect with an increase in salivary secretion

  • Y. Hayashi

      Affiliations

    • Department of Cariology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki 852-8588, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 95 849 7677; fax: +81 95 849 7680.
    • ,
  • N. Ohara

      Affiliations

    • Department of Cariology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki 852-8588, Japan
    • Department of Crown and Bridge, Nihon University School of Dentistry, Tokyo 101-8310, Japan
    • ,
  • T. Ganno

      Affiliations

    • Department of Cariology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki 852-8588, Japan
    • ,
  • H. Ishizaki

      Affiliations

    • Department of Cariology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki 852-8588, Japan
    • ,
  • K. Yanagiguchi

      Affiliations

    • Department of Cariology, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto 1-7-1, Nagasaki 852-8588, Japan

Received 27 June 2007 ,Revised 16 August 2007 ,Accepted 18 August 2007.

References 

  1. Cragg GM, Newman DJ, Snader KM. Natural products in drug discovery and development. Journal of Natural Products. 1997;60:52–60
  2. Wu-Yuan CD, Chen CY, Wu RT. Gallotannins inhibits growth, water-insoluble glucan synthesis and aggregation of mutans streptococci. Journal of Dental Research. 1988;67:51–55
  3. Fujiwara M, Hayashi Y, Ohara N. Inhibitory effect of water-soluble chitosan on growth of Streprococcus mutans. New Microbiologica. 2004;27:83–86
  4. Oh HI, Kim YJ, Chang EJ, Kim JY. Antimicrobial characteristics of chitosan against food spoilage microorganisms in liquid media and mayonnaise. Bioscience, Biotechnology and Biochemistry. 2001;65:2378–2383
  5. Helander IM, Latva-Kala K, Lounatmaa K. Permeabilizing action of polyethyleneimine on Salmonella typhimurium involves disruption of the outer membrane and interactions with lipopolysaccharide. Microbiology. 2003;344:385–390
  6. Vishu Kumar AB, Varadaraj MC, Gowda LR, Tharnathan RN. Characterization of chito-oligosaccharides prepared by chitosanolysis with the aid of papain and pronase, and their bactericidal action against Bacillus cereus and Escherichia coli. Biochemical Journal. 2005;391:167–175
  7. Voet J, Voet D. Biochemistry. 2nd ed.. New York: Wiley; 1995.;p. 360–2
  8. Sano H, Shibasaki K, Matsukubo T, Takaesu Y. Effect of chitosan rinsing on reduction of dental plaque formation. Bulletin of Tokyo Dental College. 2003;44:9–16
  9. Bae K, Jun EJ, Lee SM, Paik DI, Kim JB. Effect of water-soluble reduced chitosan on Streptococcus mutans, plaque regrowth and biofilm vitality. Clinical Oral Investigations. 2006;10:102–107
  10. Hayashi Y, Ohara N, Ganno T, Yamaguchi K, Ishizaki T, Nakamura T, et al. Chewing chitosan-containing gum effectively inhibits the growth of cariogenic bacteria. Archives of Oral Biolology. 2007;52:290–294
  11. Volker JF. The effect of chewing gum on the teeth and supporting structures. Journal of American Dental Association. 1948;36:23–27
  12. Suzuki K, Wada M, Nagai S, Nagajama F, Niwa Y, Sato Y, et al. Changes in flow rate and pH of whole saliva following gum chewing. Japanese Journal of Conservative Dentistry. 1979;22:136–143[in Japanese]
  13. Itthagarum A, Wei SHY. Chewing gum and saliva in oral health. Journal of Clinical Dentistry. 1997;8:159–162
  14. Hanham A, Addy M. The effect of chewing sugar-free gum on plaque regrowth at smooth and occlusal surfaces. Journal of Clinical Periodontology. 2001;28:255–257
  15. No HK, Park NY, Kee SH, Meyers SP. Antibacterial activity of chitosans and chitosan oligomers with different molecular weights. International Journal of Food Microbiology. 2002;74:65–72
  16. Dawes C. Factors influencing salivary flow rate and composition. In:  Edgar WM,  O’Mullane DM editor. Saliva and oral health. 2nd ed.. London: British Dental Association; 1996;p. 27–41
  17. Hodoba D. Chewing can relieve sleepiness in a night of sleep deprivation. Sleep Research Online. 1999;2:101–105
  18. Britt DM, Cohen LM, Collins FL, Cohen ML. Cigarette smoking and chewing gum: response to a laboratory-induced stressor. Health Psychology. 2001;20:361–368
  19. Hirayama I, Suzuki M, Ide M, Aso T, Kuwano H. Gum-chewing stimulates bowel motility after surgery for colorectal cancer. Hepatogastroenterology. 2006;53:206–208
  20. Kohler M, Pavy A, van den Heuvel C. The effects of chewing versus caffeine on alertness, cognitive performance and cardiac autonomic activity during sleep deprivation. Journal of Sleep Research. 2006;15:358–368

PII: S0300-5712(07)00161-3

doi: 10.1016/j.jdent.2007.08.004

Journal of Dentistry
Volume 35, Issue 11 , Pages 871-874 , November 2007

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