Journal of Dentistry
Volume 35, Issue 11 , Pages 851-857 , November 2007

Effect of various calcium/phosphates ratios of carboxymethylcellulose-based saliva substitutes on mineral loss of bovine enamel in vitro

  • Hendrik Meyer-Lueckel

      Affiliations

    • Department of Operative Dentistry and Periodontology, University School of Dental Medicine, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Germany
  • ,
  • Andreas J. Chatzidakis

      Affiliations

    • Department of Prosthetic Dentistry, University School for Dental Medicine, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Germany
    • Corresponding Author InformationCorresponding author at: Department of Prosthetic Dentistry, Charité Centrum 3 of Dental Medicine, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Assmannshauser Strasse 4-6, 14197 Berlin, Germany. Tel.: +49 30 8445 6220/6244; fax: +49 30 8445 6238.
  • ,
  • Andrej M. Kielbassa

      Affiliations

    • Department of Operative Dentistry and Periodontology, University School of Dental Medicine, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Germany

Received 18 June 2007 ,Revised 13 August 2007 ,Accepted 13 August 2007.

References 

  1. Sreebny LM. Recognition and treatment of salivary induced conditions. International Dental Journal. 1989;39:197–204
  2. Atkinson JC, Grisius M, Massey W. Salivary hypofunction and xerostomia: diagnosis and treatment. Dental Clinics of North America. 2005;49:309–326
  3. Soto-Rojas AE, Kraus A. The oral side of Sjogren syndrome. Diagnosis and treatment. A review. Archives of Medical Research. 2002;33:95–106
  4. Vissink A, Burlage FR, Spijkervet FK, Jansma J, Coppes RP. Prevention and treatment of the consequences of head and neck radiotherapy. Critical Reviews in Oral Biology and Medicine. 2003;14:213–225
  5. Kielbassa AM, Hinkelbein W, Hellwig E, Meyer-Lueckel H. Radiation-related damage to dentition. Lancet Oncology. 2006;7:326–335
  6. Guchelaar HJ, Vermes A, Meerwaldt JH. Radiation-induced xerostomia: pathophysiology, clinical course and supportive treatment. Supportive Care in Cancer. 1997;5:281–288
  7. Shannon IL, Trodahl JN, Starcke EN. Remineralization of enamel by a saliva substitute designed for use by irradiated patients. Cancer. 1978;41:1746–1750
  8. Meyer-Lueckel H, Tschoppe P, Kielbassa AM. Linseed-based saliva substitutes and their effect on mineral dissolution of predemineralized bovine dentin in vitro. Journal of Dentistry. 2006;34:751–756
  9. Meyer-Lueckel H, Hopfenmuller W, von Klinggraff D, Kielbassa AM. Microradiographic study on the effects of mucin-based solutions used as saliva substitutes on demineralised bovine enamel in vitro. Archives of Oral Biology. 2006;51:541–547
  10. Meyer-Lueckel H, Kielbassa AM. Influence of calcium phosphates added to mucin-based saliva substitutes on bovine dentin. Quintessence International: Journal of Practical Dentistry. 2006;37:537–544
  11. Kielbassa AM, Shohadai SP, Schulte-Monting J. Effect of saliva substitutes on mineral content of demineralized and sound dental enamel. Supportive Care in Cancer. 2001;9:40–47
  12. Smith G, Smith AJ, Shaw L, Shaw MJ. Artificial saliva substitutes and mineral dissolution. Journal of Oral Rehabilitation. 2001;28:728–731
  13. Meyer-Lueckel H, Schulte-Monting J, Kielbassa AM. The effect of commercially available saliva substitutes on predemineralized bovine dentin in vitro. Oral Diseases. 2002;8:192–198
  14. Buskes JAKM, Christofferson J, Arends J. Lesion formation and lesion remineralization in enamel under constant composition conditions. A new technique with application. Caries Research. 1985;19:490–496
  15. Kielbassa AM, Schendera A, Schulte-Monting J. Microradiographic and microscopic studies on in situ induced initial caries in irradiated and nonirradiated dental enamel. Caries Research. 2000;34:41–47
  16. Shellis RP. A microcomputer program to evaluate the saturation of complex solutions with respect to biominerals. Computer Applications in the Biosciences. 1988;4:373–379
  17. Dreizen S, Brown LR, Handler S, Levy BM. Radiation-induced xerostomia in cancer patients. Effect on salivary and serum electrolytes. Cancer. 1976;38:273–278
  18. Larsen MJ, Pearce EI. Saturation of human saliva with respect to calcium salts. Archives of Oral Biology. 2003;48:317–322
  19. Ben-Aryeh H, Gutman D, Szargel R, Laufer D. Effects of irradiation on saliva in cancer patients. International Journal of Oral & Maxillofacial Surgery. 1975;4:205–210
  20. Vissink A, s’Gravenmade EJ, Gelhard TB, Panders AK, Franken MH. Rehardening properties of mucin- or CMC-containing saliva substitutes on softened human enamel. Effects of sorbitol, xylitol and increasing viscosity. Caries Research. 1985;19:212–218
  21. Featherstone JD. Diffusion phenomena and enamel caries development. Basel: Karger; 1984;
  22. Hatton MN, Levine MJ, Margarone JE, Aguirre A. Lubrication and viscosity features of human saliva and commercially available saliva substitutes. Journal of Oral and Maxillofacial Surgery. 1987;45:496–499
  23. Mellberg JR. Hard-tissue substrates for evaluation of cariogenic and anti-cariogenic activity in situ. Journal of Dental Research. 1992;71:913–919
  24. Featherstone JD. Modeling the caries-inhibitory effects of dental materials. Dental Materials. 1996;12:194–197
  25. Chow LC. Solubility of calcium phosphates. Monographs in Oral Science. 2001;18:94–111
  26. Nancollas GH, Tomazic B. Growth of calcium phosphate on hydroxyapatite crystals. Effect of supersaturation and ionic medium. The Journal of Physical Chemistry. 1974;78:2218–2225
  27. Gelhard TB, Fidler V, s’Gravenmade EJ, Vissink A. Remineralization of softened human enamel in mucin- or CMC-containing artificial salivas. Journal of Oral Pathology and Medicine. 1983;12:336–341
  28. Featherstone JD, Duncan JF, Cutress TW. A mechanism for dental caries based on chemical processes and diffusion phenomena during in vitro caries simulation on human tooth enamel. Archives of Oral Biology. 1979;24:101–112
  29. Meyer-Lueckel H, Tschoppe P, Kielbassa AM. Effect of various Ca(2+)/PO4(3−) concentrations of linseed-based saliva substitutes on enamel in vitro. Journal of Oral Rehabilitation. 2006;33:760–766
  30. Tanaka M, Kadoma Y. Comparative reduction of enamel demineralization by calcium and phosphate in vitro. Caries Research. 2000;34:241–245

PII: S0300-5712(07)00146-7

doi: 10.1016/j.jdent.2007.08.006

Journal of Dentistry
Volume 35, Issue 11 , Pages 851-857 , November 2007